Inhibitors | Comment | Organism | Structure |
---|---|---|---|
P-407 | - |
Mus musculus |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Mus musculus | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
placenta | - |
Mus musculus | - |
Synonyms | Comment | Organism |
---|---|---|
LPL | - |
Mus musculus |
General Information | Comment | Organism |
---|---|---|
malfunction | lipoprotein lipase knock-out mice die 18 h after birth, probably because of hypoglycemia | Mus musculus |
metabolism | lipoprotein lipase is a major enzyme in lipid metabolism responsible for the hydrolysis of the core triglycerides in chylomicrons and very low density lipoprotein and subsequent release of free fatty acids | Mus musculus |
physiological function | lipoprotein lipase LPL expressed in placenta facilitates uptake of retinoids by this organ and their transfer to the embryo, mainly through its catalytic activity. In addition, LPL can mediate the acquisition of nascent chylomicrons by the placenta, although less efficiently. Placental LPL acts in concert with low density lipoprotein receptor and LRP1 | Mus musculus |