Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | Homo sapiens | monoglyceride lipase does exhibit PLA1 activity | ? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Purification (Comment) | Organism |
---|---|
native enzyme 1500fold from thrombin-activated platelets by anion exchange, hydrophobic interaction, and affinity chromatography | Homo sapiens |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
blood platelet | - |
Homo sapiens | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | monoglyceride lipase does exhibit PLA1 activity | Homo sapiens | ? | - |
? | |
phosphatidylcholine + H2O | - |
Homo sapiens | lysophosphatidylcholine + fatty acid | - |
? | |
phosphatidylserine + H2O | - |
Homo sapiens | lysophosphatidylserine + fatty acid | - |
? |
Synonyms | Comment | Organism |
---|---|---|
PLA 1 | - |
Homo sapiens |
Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
---|---|---|---|
37 | - |
assay at | Homo sapiens |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
7.5 | - |
assay at | Homo sapiens |
General Information | Comment | Organism |
---|---|---|
physiological function | the phospholipase A1 activity of lysophospholipase A-I links platelet activation to LPA production during blood coagulation | Homo sapiens |