Literature summary for 3.1.1.31 extracted from

Delarue, M.; Duclert-Savatier, N.; Miclet, E.; Haouz, A.; Giganti, D.; Ouazzani, J.; Lopez, P.; Nilges, M.; Stoven, V.
Three dimensional structure and implications for the catalytic mechanism of 6-phosphogluconolactonase from Trypanosoma brucei (2007), J. Mol. Biol., 366, 868-881.

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Crystallization (Commentary)

Crystallization (Comment)	Organism
hanging-drop method, equilibrated against a reservoir solution of 100 mM Hepes (pH 7.5), 30% (v/v) PEG MME 2000, 50 mM sodium acetate	Trypanosoma brucei

Localization

Localization	Comment	Organism	GeneOntology No.	Textmining
glycosome	-	Trypanosoma brucei	20015	-

Metals/Ions

Metals/Ions	Comment	Organism	Structure
Zn	each monomer binds one Zn-atom, far away from catalytic site, plays structural role	Trypanosoma brucei

Molecular Weight [Da]

Molecular Weight [Da]	Molecular Weight Maximum [Da]	Comment	Organism
30000	-	-	Trypanosoma brucei

Natural Substrates/ Products (Substrates)

Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
delta-6 phosphogluconolactone + H2O	Trypanosoma brucei	-	6-phosphogluconic acid	-	?

Organism

Organism	UniProt	Comment	Textmining
Trypanosoma brucei	Q385D6	-	-

Purification (Commentary)

Purification (Comment)	Organism
purified to 95% homogeneity in a single step with a Co-NTA column	Trypanosoma brucei

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
delta-6 phosphogluconolactone + H2O	-	Trypanosoma brucei	6-phosphogluconic acid	-	?

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Release 2023.1 (January 2023)