Literature summary for 3.1.1.23 extracted from

Keimpema, E.; Barabas, K.; Morozov, Y.M.; Tortoriello, G.; Torii, M.; Cameron, G.; Yanagawa, Y.; Watanabe, M.; Mackie, K.; Harkany, T.
Differential subcellular recruitment of monoacylglycerol lipase generates spatial specificity of 2-arachidonoyl glycerol signaling during axonal pathfinding (2010), J. Neurosci., 30, 13992-14007.

Search for more literature for 3.1.1.23

Organism

Organism	UniProt	Comment	Textmining
Mus musculus	-	-	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
brain	MGL is expressed in central and peripheral axons of the fetal nervous system by embryonic day 12.5. MGL coexists with sn-1-diacylglycerol lipase alpha and CB1 cannabinoid receptors in corticofugal axons of pyramidal cells	Mus musculus	-
brain cortex	MGL and CB1 cannabinoid receptors are coexpressed in corticofugal but not thalamocortical axons	Mus musculus	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
2-arachidonoylglycerol + H2O	-	Mus musculus	glycerol + arachidonic acid	-	?

Synonyms

Synonyms	Comment	Organism
MGL	-	Mus musculus
monoacylglycerol lipase	-	Mus musculus

General Information

General Information	Comment	Organism
malfunction	MGL inactivation drives a CB1 cannabinoid receptor-dependent axonal growth response	Mus musculus

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Release 2023.1 (January 2023)