Cloned (Comment) | Organism |
---|---|
- |
Mus musculus |
- |
Homo sapiens |
- |
Rattus norvegicus |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
4-nitrophenyl 4-[bis(1,3-benzodioxol-5-yl)hydroxymethyl]piperidine-1-carboxylate | JZL184 | Homo sapiens | |
4-nitrophenyl 4-[bis(1,3-benzodioxol-5-yl)hydroxymethyl]piperidine-1-carboxylate | JZL184 | Mus musculus | |
4-nitrophenyl 4-[bis(1,3-benzodioxol-5-yl)hydroxymethyl]piperidine-1-carboxylate | JZL184 | Rattus norvegicus | |
methyl arachidonyl fluorophosphonate | MAFP | Homo sapiens | |
methyl arachidonyl fluorophosphonate | MAFP | Mus musculus | |
methyl arachidonyl fluorophosphonate | MAFP | Rattus norvegicus | |
[4-(5-methoxy-2-oxo-1,3,4-oxadiazol-3-yl)-2-methylphenyl]carbamic acid benzyl ester | CAY10499 | Homo sapiens | |
[4-(5-methoxy-2-oxo-1,3,4-oxadiazol-3-yl)-2-methylphenyl]carbamic acid benzyl ester | CAY10499 | Mus musculus | |
[4-(5-methoxy-2-oxo-1,3,4-oxadiazol-3-yl)-2-methylphenyl]carbamic acid benzyl ester | CAY10499 | Rattus norvegicus |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
cytosol | - |
Mus musculus | 5829 | - |
cytosol | - |
Homo sapiens | 5829 | - |
cytosol | - |
Rattus norvegicus | 5829 | - |
membrane | - |
Mus musculus | 16020 | - |
membrane | - |
Homo sapiens | 16020 | - |
membrane | - |
Rattus norvegicus | 16020 | - |
Organic Solvent | Comment | Organism |
---|---|---|
Triton X-100 | - |
Mus musculus |
Triton X-100 | - |
Homo sapiens |
Triton X-100 | - |
Rattus norvegicus |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Mus musculus | - |
- |
- |
Rattus norvegicus | - |
- |
- |
Purification (Comment) | Organism |
---|---|
- |
Homo sapiens |
- |
Rattus norvegicus |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
brain | - |
Mus musculus | - |
brain | - |
Rattus norvegicus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
1,3-dihydroxypropan-2-yl 4-pyren-1-ylbutanoate | - |
Mus musculus | pyrenylbutanoic acid + glycerol | - |
? | |
1,3-dihydroxypropan-2-yl 4-pyren-1-ylbutanoate | - |
Rattus norvegicus | pyrenylbutanoic acid + glycerol | - |
? | |
1,3-dihydroxypropan-2-yl 4-pyren-1-ylbutanoate + H2O | - |
Homo sapiens | pyrenylbutanoic acid + glycerol | - |
? | |
2-arachidonoylglycerol + H2O | - |
Mus musculus | arachidonic acid + glycerol | - |
? | |
2-arachidonoylglycerol + H2O | - |
Homo sapiens | arachidonic acid + glycerol | - |
? | |
2-arachidonoylglycerol + H2O | - |
Rattus norvegicus | arachidonic acid + glycerol | - |
? |
Synonyms | Comment | Organism |
---|---|---|
MAGL | - |
Mus musculus |
MAGL | - |
Homo sapiens |
MAGL | - |
Rattus norvegicus |
monoacylglycerol lipase | - |
Mus musculus |
monoacylglycerol lipase | - |
Homo sapiens |
monoacylglycerol lipase | - |
Rattus norvegicus |
IC50 Value | IC50 Value Maximum | Comment | Organism | Inhibitor | Structure |
---|---|---|---|---|---|
0.000033 | - |
at 37°C, pH 7.0, incubation time of 15 min, without Triton X-100 | Homo sapiens | methyl arachidonyl fluorophosphonate | |
0.000062 | - |
at 37°C, pH 7.0, incubation time of 15 min, in the presence of 0.2% (m/v) Triton X-100 | Homo sapiens | methyl arachidonyl fluorophosphonate | |
0.00016 | - |
at 37°C, pH 7.0, incubation time of 15 min, in the presence of 0.2% (m/v) Triton X-100 | Homo sapiens | methyl arachidonyl fluorophosphonate | |
0.00021 | - |
at 37°C, pH 7.0, incubation time of 15 min, without Triton X-100 | Homo sapiens | 4-nitrophenyl 4-[bis(1,3-benzodioxol-5-yl)hydroxymethyl]piperidine-1-carboxylate | |
0.00048 | - |
at 37°C, pH 7.0, incubation time of 15 min, in the presence of 0.2% (m/v) Triton X-100 | Homo sapiens | [4-(5-methoxy-2-oxo-1,3,4-oxadiazol-3-yl)-2-methylphenyl]carbamic acid benzyl ester | |
0.00061 | - |
at 37°C, pH 7.0, incubation time of 15 min, without Triton X-100 | Homo sapiens | [4-(5-methoxy-2-oxo-1,3,4-oxadiazol-3-yl)-2-methylphenyl]carbamic acid benzyl ester | |
0.0011 | - |
at 37°C, pH 7.0, incubation time of 15 min, in the presence of 0.2% (m/v) Triton X-100 | Homo sapiens | [4-(5-methoxy-2-oxo-1,3,4-oxadiazol-3-yl)-2-methylphenyl]carbamic acid benzyl ester | |
0.0017 | - |
at 37°C, pH 7.0, incubation time of 15 min, in the presence of 0.2% (m/v) Triton X-100 | Homo sapiens | 4-nitrophenyl 4-[bis(1,3-benzodioxol-5-yl)hydroxymethyl]piperidine-1-carboxylate | |
0.0037 | - |
at 37°C, pH 7.0, incubation time of 15 min, in the presence of 0.2% (m/v) Triton X-100 | Homo sapiens | 4-nitrophenyl 4-[bis(1,3-benzodioxol-5-yl)hydroxymethyl]piperidine-1-carboxylate |