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Literature summary for 3.1.1.23 extracted from

  • Dinh, T.P.; Freund, T.F.; Piomelli, D.
    A role for monoglyceride lipase in 2-arachidonoylglycerol inactivation (2002), Chem. Phys. Lipids, 121, 149-158.
    View publication on PubMed
Search for more literature for 3.1.1.23

Cloned(Commentary)

Cloned (Comment) Organism
expressed in COS-7 and HeLa cells Rattus norvegicus

Inhibitors

Inhibitors Comment Organism Structure
arachidonoyl trifluoromethylketone 50% inhibition at 0.0025 mM Rattus norvegicus
hexadecylsufonyl fluoride 50% inhibition at 0.0062 mM Rattus norvegicus
methyl arachidonyl fluorophosphonate 50% inhibition at 0.0008 mM Rattus norvegicus

Localization

Localization Comment Organism GeneOntology No. Textmining
cytosol after expression in HeLa cells Rattus norvegicus 5829
-
plasma membrane after expression in HeLa cells Rattus norvegicus 5886
-

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
33370
-
 calculated from amino acid sequence Rattus norvegicus
35000
-
 two isoforms of 35000 Da and 37000 Da, SDS-PAGE Rattus norvegicus
37000
-
 two isoforms of 35000 Da and 37000 Da, SDS-PAGE Rattus norvegicus

Organism

Organism UniProt Comment Textmining
Rattus norvegicus
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
brain
-
 Rattus norvegicus
-
cerebellum
-
 Rattus norvegicus
-
cerebral cortex
-
 Rattus norvegicus
-
hippocampus
-
 Rattus norvegicus
-
thalamus
-
 Rattus norvegicus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2-arachidonoylglycerol + H2O
-
 Rattus norvegicus arachidonic acid + glycerol
-
 ?
2-monooleoylglycerol + H2O
-
 Rattus norvegicus oleic acid + glycerol
-
 r