Any feedback?
Literature summary for 2.8.3.5 extracted from
- The role of 3-oxo acid-CoA transferase in the regulation of ketogenesis in the liver (1979), FEBS Lett., 103, 212-215.
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| succinyl-CoA + acetoacetate | Gallus gallus | liver enzyme: produces a substrate circle between acetoacetyl-CoA and acetoacetate | ? | - |
? |  |
| succinyl-CoA + acetoacetate | Mus musculus | liver enzyme: produces a substrate circle between acetoacetyl-CoA and acetoacetate | ? | - |
? | |
| succinyl-CoA + acetoacetate | Rattus norvegicus | liver enzyme: produces a substrate circle between acetoacetyl-CoA and acetoacetate | ? | - |
? | |
| succinyl-CoA + acetoacetate | Oryctolagus cuniculus | liver enzyme: produces a substrate circle between acetoacetyl-CoA and acetoacetate | ? | - |
? | |
| succinyl-CoA + acetoacetate | Oncorhynchus mykiss | liver enzyme: produces a substrate circle between acetoacetyl-CoA and acetoacetate | ? | - |
? | |
| succinyl-CoA + acetoacetate | Columba livia | liver enzyme: produces a substrate circle between acetoacetyl-CoA and acetoacetate | ? | - |
? | |
| succinyl-CoA + acetoacetate | Scyliorhinus canicula | liver enzyme: produces a substrate circle between acetoacetyl-CoA and acetoacetate | ? | - |
? | |
| succinyl-CoA + acetoacetate | Dicentrarchus labrax | liver enzyme: produces a substrate circle between acetoacetyl-CoA and acetoacetate | ? | - |
? | |
| succinyl-CoA + acetoacetate | Pleuronectes platessa | liver enzyme: produces a substrate circle between acetoacetyl-CoA and acetoacetate | ? | - |
? | |
| succinyl-CoA + acetoacetate | Raja clavata | liver enzyme: produces a substrate circle between acetoacetyl-CoA and acetoacetate | ? | - |
? | |
| succinyl-CoA + acetoacetate | Clupea harengus | liver enzyme: produces a substrate circle between acetoacetyl-CoA and acetoacetate | ? | - |
? | |
| succinyl-CoA + acetoacetate | Lacerta viridis | liver enzyme: produces a substrate circle between acetoacetyl-CoA and acetoacetate | ? | - |
? | |
| succinyl-CoA + acetoacetate | Scomber scombrus | liver enzyme: produces a substrate circle between acetoacetyl-CoA and acetoacetate | ? | - |
? | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Clupea harengus | - |
herring | - |
| Columba livia | - |
domestic pigeon | - |
| Dicentrarchus labrax | - |
bass | - |
| Gallus gallus | - |
domestic fowl | - |
| Lacerta viridis | - |
green lizard | - |
| Mus musculus | - |
- |
- |
| Oncorhynchus mykiss | - |
rainbow trout | - |
| Oryctolagus cuniculus | - |
- |
- |
| Pleuronectes platessa | - |
plaice | - |
| Raja clavata | - |
ray | - |
| Rattus norvegicus | - |
- |
- |
| Scomber scombrus | - |
mackerel | - |
| Scyliorhinus canicula | - |
dogfish | - |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| liver | - |
Gallus gallus | - |
| liver | - |
Mus musculus | - |
| liver | - |
Rattus norvegicus | - |
| liver | - |
Oryctolagus cuniculus | - |
| liver | - |
Oncorhynchus mykiss | - |
| liver | - |
Columba livia | - |
| liver | - |
Scyliorhinus canicula | - |
| liver | - |
Dicentrarchus labrax | - |
| liver | - |
Pleuronectes platessa | - |
| liver | - |
Raja clavata | - |
| liver | - |
Clupea harengus | - |
| liver | - |
Lacerta viridis | - |
| liver | - |
Scomber scombrus | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| succinyl-CoA + acetoacetate | - |
Gallus gallus | succinate + acetoacetyl-CoA | - |
? | |
| succinyl-CoA + acetoacetate | - |
Mus musculus | succinate + acetoacetyl-CoA | - |
? | |
| succinyl-CoA + acetoacetate | - |
Rattus norvegicus | succinate + acetoacetyl-CoA | - |
? | |
| succinyl-CoA + acetoacetate | - |
Oryctolagus cuniculus | succinate + acetoacetyl-CoA | - |
? | |
| succinyl-CoA + acetoacetate | - |
Oncorhynchus mykiss | succinate + acetoacetyl-CoA | - |
? | |
| succinyl-CoA + acetoacetate | - |
Columba livia | succinate + acetoacetyl-CoA | - |
? | |
| succinyl-CoA + acetoacetate | - |
Scyliorhinus canicula | succinate + acetoacetyl-CoA | - |
? | |
| succinyl-CoA + acetoacetate | - |
Dicentrarchus labrax | succinate + acetoacetyl-CoA | - |
? | |
| succinyl-CoA + acetoacetate | - |
Pleuronectes platessa | succinate + acetoacetyl-CoA | - |
? | |
| succinyl-CoA + acetoacetate | - |
Raja clavata | succinate + acetoacetyl-CoA | - |
? | |
| succinyl-CoA + acetoacetate | - |
Clupea harengus | succinate + acetoacetyl-CoA | - |
? | |
| succinyl-CoA + acetoacetate | - |
Lacerta viridis | succinate + acetoacetyl-CoA | - |
? | |
| succinyl-CoA + acetoacetate | - |
Scomber scombrus | succinate + acetoacetyl-CoA | - |
? | |
| succinyl-CoA + acetoacetate | liver enzyme: produces a substrate circle between acetoacetyl-CoA and acetoacetate | Gallus gallus | ? | - |
? | |
| succinyl-CoA + acetoacetate | liver enzyme: produces a substrate circle between acetoacetyl-CoA and acetoacetate | Mus musculus | ? | - |
? | |
| succinyl-CoA + acetoacetate | liver enzyme: produces a substrate circle between acetoacetyl-CoA and acetoacetate | Rattus norvegicus | ? | - |
? | |
| succinyl-CoA + acetoacetate | liver enzyme: produces a substrate circle between acetoacetyl-CoA and acetoacetate | Oryctolagus cuniculus | ? | - |
? | |
| succinyl-CoA + acetoacetate | liver enzyme: produces a substrate circle between acetoacetyl-CoA and acetoacetate | Oncorhynchus mykiss | ? | - |
? | |
| succinyl-CoA + acetoacetate | liver enzyme: produces a substrate circle between acetoacetyl-CoA and acetoacetate | Columba livia | ? | - |
? | |
| succinyl-CoA + acetoacetate | liver enzyme: produces a substrate circle between acetoacetyl-CoA and acetoacetate | Scyliorhinus canicula | ? | - |
? | |
| succinyl-CoA + acetoacetate | liver enzyme: produces a substrate circle between acetoacetyl-CoA and acetoacetate | Dicentrarchus labrax | ? | - |
? | |
| succinyl-CoA + acetoacetate | liver enzyme: produces a substrate circle between acetoacetyl-CoA and acetoacetate | Pleuronectes platessa | ? | - |
? | |
| succinyl-CoA + acetoacetate | liver enzyme: produces a substrate circle between acetoacetyl-CoA and acetoacetate | Raja clavata | ? | - |
? | |
| succinyl-CoA + acetoacetate | liver enzyme: produces a substrate circle between acetoacetyl-CoA and acetoacetate | Clupea harengus | ? | - |
? | |
| succinyl-CoA + acetoacetate | liver enzyme: produces a substrate circle between acetoacetyl-CoA and acetoacetate | Lacerta viridis | ? | - |
? | |
| succinyl-CoA + acetoacetate | liver enzyme: produces a substrate circle between acetoacetyl-CoA and acetoacetate | Scomber scombrus | ? | - |
? | |
Temperature Optimum [°C]
| Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
|---|---|---|---|
| 10 | - |
assay at, all fish enzymes except Salmo gairdneri | Scyliorhinus canicula |
| 10 | - |
assay at, all fish enzymes except Salmo gairdneri | Dicentrarchus labrax |
| 10 | - |
assay at, all fish enzymes except Salmo gairdneri | Pleuronectes platessa |
| 10 | - |
assay at, all fish enzymes except Salmo gairdneri | Raja clavata |
| 10 | - |
assay at, all fish enzymes except Salmo gairdneri | Clupea harengus |
| 10 | - |
assay at, all fish enzymes except Salmo gairdneri | Scomber scombrus |
| 25 | - |
assay at | Gallus gallus |
| 25 | - |
assay at | Mus musculus |
| 25 | - |
assay at | Rattus norvegicus |
| 25 | - |
assay at | Oryctolagus cuniculus |
| 25 | - |
assay at | Oncorhynchus mykiss |
| 25 | - |
assay at | Columba livia |
| 25 | - |
assay at | Lacerta viridis |
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