Activating Compound | Comment | Organism | Structure |
---|---|---|---|
Sodium sulfate | increases the activity at 1 mM | Sus scrofa |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
ADP | - |
Sus scrofa | |
coenzyme A | - |
Sus scrofa | |
desulfo-CoA | competitive inhibition with respect to acetoacetyl-CoA | Sus scrofa | |
desulfopantetheine | competitive inhibition with respect to acetoacetyl-CoA | Sus scrofa | |
N-acetylaletheine | reacts with the enzyme thiol ester E-CoA to form a catalytically inactive enzyme | Sus scrofa | |
N-acetylcysteamine | reacts with the enzyme thiol ester E-CoA to form a catalytically inactive enzyme | Sus scrofa | |
pantothenol | - |
Sus scrofa |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.0002 | - |
acetoacetate | pH 8.1, 25°C, presence of sodium sulfate | Sus scrofa |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Sus scrofa | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
heart | - |
Sus scrofa | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
succinyl-CoA + acetoacetate | - |
Sus scrofa | succinate + acetoacetyl-CoA | - |
? |
Ki Value [mM] | Ki Value maximum [mM] | Inhibitor | Comment | Organism | Structure |
---|---|---|---|---|---|
1.7 | - |
CoA | pH 8.1, 25° | Sus scrofa | |
2.7 | - |
desulfo-CoA | pH 8.1, 25° | Sus scrofa | |
45 | - |
ADP | pH 8.1, 25° | Sus scrofa | |
110 | - |
desulfopoantetheine | pH 8.1, 25° | Sus scrofa | |
120 | - |
pantothenol | pH 8.1, 25° | Sus scrofa |