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Literature summary for 2.8.3.5 extracted from
- Diabetes-associated nitration of tyrosine and inactivation of succinyl-CoA:3-oxoacid CoA-transferase (2001), Am. J. Physiol., 281, H2289-H2294.
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| streptozotocin | in vivo catalytic activity decreases after 4 and 8 weeks of treatment with streptozotocin | Rattus norvegicus |  |
Localization
| Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|
| mitochondrion | - |
Rattus norvegicus | 5739 | - |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Rattus norvegicus | - |
male Sprague-Dawley | - |
Posttranslational Modification
| Posttranslational Modification | Comment | Organism |
|---|---|---|
| additional information | basal nitration only detectable in heart and kidney, nitration in heart occurs after streptozotocin-treatment | Rattus norvegicus |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| heart | - |
Rattus norvegicus | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| succinyl-CoA + acetoacetate | - |
Rattus norvegicus | succinate + acetoacetyl-CoA | - |
? | |
pH Optimum
| pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|
| 8 | - |
assay at | Rattus norvegicus |
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Release 2023.1 (January 2023)
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