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Literature summary for 2.8.3.11 extracted from
- Efficient conversion of itaconic acid to (S)-(+)-citramalic acid by Alcaligenes xylosoxydans IL 142 (2000), J. Biosci. Bioeng., 89, 388-391.
Activating Compound
| Activating Compound | Comment | Organism | Structure |
|---|---|---|---|
| ATP | activity is enhanced in presence of CoA and succinate | Achromobacter xylosoxidans |  |
| CoA | activity is enhanced in presence of ATP and succinate | Achromobacter xylosoxidans | |
| succinate | activity is enhanced in presence of CoA and ATP | Achromobacter xylosoxidans | |
Application
| Application | Comment | Organism |
|---|---|---|
| biotechnology | production process of enantiomeric pure (S)-(+)-citramalic acid from itaconic acid | Achromobacter xylosoxidans |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| succinate + (S)-(+)-citramalyl-CoA | Achromobacter xylosoxidans | 99.9% enantiomeric purity | succinyl-CoA + citramalate | - |
r | |
| succinate + (S)-(+)-citramalyl-CoA | Achromobacter xylosoxidans IL142 | 99.9% enantiomeric purity | succinyl-CoA + citramalate | - |
r | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Achromobacter xylosoxidans | - |
- |
- |
| Achromobacter xylosoxidans IL142 | - |
- |
- |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| succinate + (3S)-citramalyl-CoA | 99.9% enantiomeric purity | Achromobacter xylosoxidans | succinyl-CoA + citramalate | - |
r | |
| succinate + (3S)-citramalyl-CoA | 99.9% enantiomeric purity | Achromobacter xylosoxidans IL142 | succinyl-CoA + citramalate | - |
r | |
| succinate + (S)-(+)-citramalyl-CoA | 99.9% enantiomeric purity | Achromobacter xylosoxidans | succinyl-CoA + citramalate | - |
r | |
| succinate + (S)-(+)-citramalyl-CoA | 99.9% enantiomeric purity | Achromobacter xylosoxidans IL142 | succinyl-CoA + citramalate | - |
r | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| citramalyl-CoA transferase | - |
Achromobacter xylosoxidans |
Temperature Optimum [°C]
| Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
|---|---|---|---|
| 35 | - |
assay at | Achromobacter xylosoxidans |
pH Optimum
| pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|
| 7.8 | - |
assay at | Achromobacter xylosoxidans |
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