Literature summary for 2.8.2.9 extracted from

Zheng, Y.; Bergold, A.; Duffel, M.W.
Affinity labeling of aryl sulfotransferase IV. Identification of a peptide sequence at the binding site for 3-phosphoadenosine-5-phosphosulfate (1994), J. Biol. Chem., 269, 30313-30319.

Search for more literature for 2.8.2.9

Cloned(Commentary)

Cloned (Comment)	Organism
rat enzyme expressed in Escherichia coli	Rattus norvegicus

Inhibitors

Inhibitors	Comment	Organism	Structure
2'-O-[(R)-formyl(adenin-9-yl)methyl]-(S)-glyceraldehyde 3'-triphosphate	ATPDA, irreversible, inhibition prevented by either adenosine 3,5'-diphosphate or 3'-phosphoadenylylsulfate, binds to Lys65 and Cys66 at the PAPS binding site	Rattus norvegicus

Organism

Organism	UniProt	Comment	Textmining
Rattus norvegicus	-	cloned and expressed in Escherichia coli	-

Purification (Commentary)

Purification (Comment)	Organism
cloned and expressed in Escherichia coli	Rattus norvegicus

Source Tissue

Source Tissue	Comment	Organism	Textmining
liver	-	Rattus norvegicus	-

Ki Value [mM]

Ki Value [mM]	Ki Value maximum [mM]	Inhibitor	Comment	Organism	Structure
0.09	-	2'-O-[(R)-formyl(adenin-9-yl)methyl]-(S)-glyceraldehyde 3'-triphosphate	pH 7, 37°C	Rattus norvegicus

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Release 2023.1 (January 2023)