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Literature summary for 2.8.2.5 extracted from

  • Bhattacharyya, S.; Feferman, L.; Tobacman, J.K.
    Regulation of chondroitin-4-sulfotransferase (CHST11) expression by opposing effects of arylsulfatase B on BMP4 and Wnt9A (2015), Biochim. Biophys. Acta, 1849, 342-352.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 2.8.2.5

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
3'-phosphoadenylyl sulfate + chondroitin Homo sapiens
-
 adenosine 3',5'-bisphosphate + chondroitin 4'-sulfate
-
 ?
3'-phosphoadenylyl sulfate + chondroitin Mus musculus
-
 adenosine 3',5'-bisphosphate + chondroitin 4'-sulfate
-
 ?

Organism

Organism UniProt Comment Textmining
Homo sapiens Q9NPF2
-
-
Mus musculus Q9JME2
-
-

Source Tissue

Source Tissue Comment Organism Textmining
colonic epithelial cell
-
 Homo sapiens
-
colonic epithelium
-
 Mus musculus
-
HT-29 cell
-
 Homo sapiens
-
NCM-460 cell
-
 Mus musculus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3'-phosphoadenylyl sulfate + chondroitin
-
 Homo sapiens adenosine 3',5'-bisphosphate + chondroitin 4'-sulfate
-
 ?
3'-phosphoadenylyl sulfate + chondroitin
-
 Mus musculus adenosine 3',5'-bisphosphate + chondroitin 4'-sulfate
-
 ?

Synonyms

Synonyms Comment Organism
C4ST
-
 Homo sapiens
C4ST
-
 Mus musculus
chondroitin-4-sulfotransferase
-
 Homo sapiens
chondroitin-4-sulfotransferase
-
 Mus musculus
CHST11
-
 Homo sapiens
CHST11
-
 Mus musculus

Expression

Organism Comment Expression
Homo sapiens a decline in arylsulfatase B reduces chondroitin-4-sulfotransferase mRNA expression. Inhibition of bone morphogenetic protein 4 also reduces enzyme expression down
Mus musculus a decline in arylsulfatase B reduces chondroitin-4-sulfotransferase mRNA expression. Inhibition of bone morphogenetic protein 4 also reduces enzyme expression down
Homo sapiens silencing Wnt9A increases the expression of CHST11 up
Mus musculus silencing Wnt9A increases the expression of CHST11 up