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Literature summary for 2.8.2.5 extracted from

  • Mitsunaga, C.; Mikami, T.; Mizumoto, S.; Fukuda, J.; Sugahara, K.
    Chondroitin sulfate/dermatan sulfate hybrid chains in the development of cerebellum. Spatiotemporal regulation of the expression of critical disulfated disaccharides by specific sulfotransferases (2006), J. Biol. Chem., 281, 18942-18952.
    View publication on PubMed
Search for more literature for 2.8.2.5

Cloned(Commentary)

Cloned (Comment) Organism
genes C4ST-1 and C4ST-2, quantitative expression analysis Sus scrofa

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
3'-phosphoadenylyl sulfate + chondroitin Sus scrofa the enzyme is involved in the biosynthesis of dermatan sulfate in addition to chondroitin sulfate intermediates adenosine 3',5'-bisphosphate + chondroitin 4'-sulfate
-
 ?
3'-phosphoadenylyl sulfate + dermatan Sus scrofa the enzyme is involved in the biosynthesis of dermatan sulfate in addition to chondroitin sulfate intermediates adenosine 3',5'-bisphosphate + dermatan 4'-sulfate
-
 ?

Organism

Organism UniProt Comment Textmining
Sus scrofa
-
 isozymes C4ST-1 and C4ST-2
-

Source Tissue

Source Tissue Comment Organism Textmining
brain C4ST-1 and C4ST-2 are ubiquitously expressed in the postnatal mouse brain, tissue distribution of expression, overview Sus scrofa
-
cerebellum
-
 Sus scrofa
-
additional information quantitative expression analysis Sus scrofa
-

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
additional information
-
 quantitative expression analysis of C4ST-1 and C4ST-2 Sus scrofa

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3'-phosphoadenylyl sulfate + chondroitin
-
 Sus scrofa adenosine 3',5'-bisphosphate + chondroitin 4'-sulfate
-
 ?
3'-phosphoadenylyl sulfate + chondroitin the enzyme is involved in the biosynthesis of dermatan sulfate in addition to chondroitin sulfate intermediates Sus scrofa adenosine 3',5'-bisphosphate + chondroitin 4'-sulfate
-
 ?
3'-phosphoadenylyl sulfate + dermatan
-
 Sus scrofa adenosine 3',5'-bisphosphate + dermatan 4'-sulfate
-
 ?
3'-phosphoadenylyl sulfate + dermatan the enzyme is involved in the biosynthesis of dermatan sulfate in addition to chondroitin sulfate intermediates Sus scrofa adenosine 3',5'-bisphosphate + dermatan 4'-sulfate
-
 ?

Synonyms

Synonyms Comment Organism
C4ST
-
 Sus scrofa
CS GalNAc 4-O-sulfotransferase
-
 Sus scrofa