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Literature summary for 2.8.2.20 extracted from

  • Jen, C.H.; Moore, K.L.; Leary, J.A.
    Pattern and temporal sequence of sulfation of CCR5 N-terminal peptides by tyrosylprotein sulfotransferase-2: an assessment of the effects of N-terminal residues (2009), Biochemistry, 48, 5332-5338.
    View publication on PubMedView publication on EuropePMC

Organism

Organism UniProt Comment Textmining
Homo sapiens
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Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3'-phosphoadenylyl sulfate + CCR5 1-18 peptide substrate is a synthetic human CCR5 peptide MDYQVSSPIYDINYYTSE-NH2. Sulfation pattern: Tyr3 is sulfated first, followed by Tyr14 or Tyr15, and finally Tyr10 Homo sapiens adenosine 3',5'-bisphosphate + sulfated CCR5 1-18peptide
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?
3'-phosphoadenylyl sulfate + CCR5 2-18 peptide substrate is a synthetic human CCR5 peptide DYQVSSPIYDINYYTSE-NH2. Sulfation pattern: Tyr14 and Tyr15 are sulfated first, followed by Tyr10, with Tyr3 sulfated last Homo sapiens adenosine 3',5'-bisphosphate + sulfated CCR5 2-18peptide
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?
3'-phosphoadenylyl sulfate + CCR8 1-17 M1A peptide substrate is a synthetic modified mouse CCR8 peptide ADYTMEPNVTMTDYYPD-NH2. Sulfation pattern: Tyr3 is sulfated first, followed by Tyr14, with Tyr15 last Homo sapiens adenosine 3',5'-bisphosphate + sulfated CCR8 1-17 M1A peptide
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?
3'-phosphoadenylyl sulfate + CCR8 2-17 M1A peptide substrate is a synthetic modified mouse CCR8 peptide DYTMEPNVTMTDYYPD-NH2. Sulfation pattern: Tyr14 is sulfated first, followed by Tyr3 and Tyr15 Homo sapiens adenosine 3',5'-bisphosphate + sulfated CCR8 2-17 M1A peptide
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?

Synonyms

Synonyms Comment Organism
TPST-2
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Homo sapiens
tyrosylprotein sulfotransferase-2
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Homo sapiens

Temperature Optimum [°C]

Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
22
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assay at room temperature Homo sapiens

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
7.2
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assay at Homo sapiens