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Literature summary for 2.8.2.1 extracted from

  • Ro, J.; Kim, H.; Shim, B.; Kim, I.; Kim, J.; Kim, H.; Cho, J.; Khadka, P.; Yun, G.; Park, K.; Park, Y.; Lee, K.; HanI, J.; Lee, J.
    In vitro metabolic modulation of aryl sulfotransferases by pharmaceutical excipients (2014), Bull. Korean Chem. Soc., 35, 2577-2580.
No PubMed abstract available

Inhibitors

Inhibitors Comment Organism Structure
Cremophor EL Ki of 3.24 mg/ml at pH 6.2 and 38°C Rattus norvegicus
Cremophor ELP
-
Rattus norvegicus
Cremophor RH40
-
Rattus norvegicus
Cremophor RH60
-
Rattus norvegicus
additional information not significantly inhibited by Lutrol F68, polyvinylpyrrolidone K-30, PEG 4000, and PEG 6000 Rattus norvegicus
sodium lauryl sulfate Ki of 0.22 mg/ml at pH 6.2 and 38°C Rattus norvegicus
Tween 20
-
Rattus norvegicus
Tween 80 Ki of 6.43 mg/ml at pH 6.2 and 38°C Rattus norvegicus

Localization

Localization Comment Organism GeneOntology No. Textmining
cytosol
-
Rattus norvegicus 5829
-

Organism

Organism UniProt Comment Textmining
Rattus norvegicus
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
liver
-
Rattus norvegicus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3'-phosphoadenylyl sulfate + 4-methylumbelliferone
-
Rattus norvegicus adenosine 3',5'-bisphosphate + 4-methylumbelliferyl sulfate
-
?

Synonyms

Synonyms Comment Organism
aryl SULT
-
Rattus norvegicus