Cloned (Comment) | Organism |
---|---|
expression of SULTs in Escherichia coli strain BL21 DE3, in Salmonella typhimurium strain TA1538, and in chinese hamster V79 cells, and application of aristolochic acid, mutagenicity with expression of different SULT isozymes and allozymes of SULT1A1, detailed overview, analysis of the expression of SULT1A1 | Homo sapiens |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
Pentachlorophenol | inhibits SULT1A1 | Homo sapiens |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
3'-phosphoadenylyl sulfate + aristolochic acid | Homo sapiens | herbal preparations containing Aristolochia species lead to progressive nephropathy and urothelial cancer in humans, metabolic activation of aristolichic acid, mutagenic effect, overview | adenosine 3',5'-bisphosphate + ? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | P50225 | SULT1A1; SULT1A1 | - |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
kidney | - |
Homo sapiens | - |
liver | - |
Homo sapiens | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
3'-phosphoadenylyl sulfate + aristolochic acid | herbal preparations containing Aristolochia species lead to progressive nephropathy and urothelial cancer in humans, metabolic activation of aristolichic acid, mutagenic effect, overview | Homo sapiens | adenosine 3',5'-bisphosphate + ? | - |
? | |
3'-phosphoadenylyl sulfate + aristolochic acid | in renal target tissue, good substrate of SULT1A1 | Homo sapiens | adenosine 3',5'-bisphosphate + ? | - |
? |
Synonyms | Comment | Organism |
---|---|---|
sulphotransferase | - |
Homo sapiens |
SULT1A1 | - |
Homo sapiens |