Inhibitors | Comment | Organism | Structure |
---|---|---|---|
2,6-Dichloro-4-nitrophenol | PI-PST and PII-PST | Homo sapiens | |
3'-phosphoadenylylsulfate | substrate inhibition | Homo sapiens | |
NaCl | PI-PST: 50% inhibition at 100 mM, PII-PST: 20% inhibition at 0.3 M | Homo sapiens |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.00035 | - |
3'-phosphoadenylylsulfate | pH 8.5 | Homo sapiens | |
0.833 | - |
tyrosylglycine | pH 8.5 | Homo sapiens |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
2 forms of P-PST: PI-PST and PII-PST | - |
Purification (Comment) | Organism |
---|---|
389fold | Homo sapiens |
phenol-sulfating form, P-PST | Homo sapiens |
Reaction | Comment | Organism | Reaction ID |
---|---|---|---|
3'-phosphoadenylyl sulfate + a phenol = adenosine 3',5'-bisphosphate + an aryl sulfate | isozyme P-PST: sequential ordered bisubstrate reaction mechanism | Homo sapiens |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
brain | - |
Homo sapiens | - |
Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|
0.0024 | - |
purified P1-PST | Homo sapiens |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
3'-phosphoadenylyl sulfate + a phenol | - |
Homo sapiens | adenosine 3',5'-bisphosphate + an aryl sulfate | - |
r | |
3'-phosphoadenylylsulfate + tyrosylglycine | - |
Homo sapiens | ? | - |
? |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
8.5 | - |
- |
Homo sapiens |
pH Minimum | pH Maximum | Comment | Organism |
---|---|---|---|
additional information | - |
- |
Homo sapiens |
Ki Value [mM] | Ki Value maximum [mM] | Inhibitor | Comment | Organism | Structure |
---|---|---|---|---|---|
0.00035 | - |
3'-phosphoadenylylsulfate | P-PST, pH 8.5 | Homo sapiens |