Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
mitochondrion | - |
Arabidopsis thaliana | 5739 | - |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Arabidopsis thaliana | O64530 | cf. EC 2.8.1.1 | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
3-mercaptopyruvate + 2 glutathione | - |
Arabidopsis thaliana | pyruvate + glutathione disulfide | - |
? | |
thiosulfate + glutathione | - |
Arabidopsis thaliana | sulfite + glutathione disulfide | - |
? |
Synonyms | Comment | Organism |
---|---|---|
AT1G79230 | - |
Arabidopsis thaliana |
General Information | Comment | Organism |
---|---|---|
metabolism | a mitochondrial sulfur catabolic pathway catalyzes the complete oxidation of L-cysteine to pyruvate and thiosulfate. After transamination to 3-mercaptopyruvate, the sulfhydryl group from L-cysteine is transferred to glutathione by sulfurtransferase Str1 and oxidized to sulfite by the sulfur dioxygenase Ethe1. Sulfite is then converted to thiosulfate by addition of a second persulfide group by sulfurtransferase 1. This pathway is most relevant during early embryo development and for vegetative growth under light-limiting conditions | Arabidopsis thaliana |
physiological function | embryo development of the thiosulfate sulfurtransferase Str1/sulfur dioxygenase Ethe1 double mutant is comparable with Str1 mutant lines and severyl impaired in comparison to wild-type. Embryogenesis is severely delayed in Str1 mutants and the Ethe1/Str1 double mutant | Arabidopsis thaliana |