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Literature summary for 2.7.8.33 extracted from
- Preparative enzymatic synthesis of polyprenyl-pyrophosphoryl-N-acetylglucosamine, an essential lipid intermediate for the biosynthesis of various bacterial cell envelope polymers (2009), Anal. Biochem., 391, 163-165.
Localization
| Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|
| membrane | integral membrane protein | Thermotoga maritima | 16020 | - |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| UDP-N-acetyl-D-glucosamine + ditrans,polycis-undecaprenyl phosphate | Thermotoga maritima | the product ditrans,polycis-undecaprenyl-N-acetyl-D-glucosaminyl diphosphate is an essential lipid intermediate for the biosynthesis of various bacterial cell envelope components | UMP + N-acetyl-D-glucosaminyldiphospho-ditrans,polycis-undecaprenol | - |
? |  |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Thermotoga maritima | Q9X1N5 | - |
- |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
- |
Thermotoga maritima |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| UDP-N-acetyl-D-glucosamine + ditrans,polycis-undecaprenyl phosphate | the product ditrans,polycis-undecaprenyl-N-acetyl-D-glucosaminyl diphosphate is an essential lipid intermediate for the biosynthesis of various bacterial cell envelope components | Thermotoga maritima | UMP + N-acetyl-D-glucosaminyldiphospho-ditrans,polycis-undecaprenol | - |
? | |
| UDP-N-acetyl-D-glucosamine + ditrans,polycis-undecaprenyl phosphate | the reverse reaction is about 1% of the forward reaction | Thermotoga maritima | UMP + N-acetyl-D-glucosaminyldiphospho-ditrans,polycis-undecaprenol | - |
? | |
| UDP-N-acetyl-D-glucosamine + heptaprenyl phosphate | - |
Thermotoga maritima | UMP + N-acetyl-D-glucosaminyldiphospho-heptaprenol | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| WecA transferase | - |
Thermotoga maritima |
Temperature Optimum [°C]
| Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
|---|---|---|---|
| 65 | - |
assay at | Thermotoga maritima |
pH Optimum
| pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|
| 8 | - |
assay at | Thermotoga maritima |
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Release 2023.1 (January 2023)
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