Application | Comment | Organism |
---|---|---|
agriculture | formation of one of the two C-P bonds in the tripeptide antibiotic bialaphos, a potent herbicide isolated from Streptomyces hygroscopicus SF1293, enzyme is produced in large amounts by high producer strain HP5-29, enzyme may contribute to improvement of bialphos production | Streptomyces hygroscopicus |
Cloned (Comment) | Organism |
---|---|
mutant NP71 constructed by gene replacement technique | Streptomyces hygroscopicus |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
carboxyphosphonoenolpyruvate | Streptomyces hygroscopicus | first natural phosphinate | (hydroxyphosphinyl)pyruvate + CO2 | - |
? | |
carboxyphosphonoenolpyruvate | Streptomyces hygroscopicus | biosynthetic pathway that leads to the tripeptide antibiotic bialaphos, formation of one of the two C-P bonds in bialaphos | (hydroxyphosphinyl)pyruvate + CO2 | - |
? | |
carboxyphosphonoenolpyruvate | Streptomyces hygroscopicus SF1293 | first natural phosphinate | (hydroxyphosphinyl)pyruvate + CO2 | - |
? | |
carboxyphosphonoenolpyruvate | Streptomyces hygroscopicus SF1293 | biosynthetic pathway that leads to the tripeptide antibiotic bialaphos, formation of one of the two C-P bonds in bialaphos | (hydroxyphosphinyl)pyruvate + CO2 | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
no activity in Streptomyces hygroscopicus | - |
- |
- |
Streptomyces hygroscopicus | - |
HP782 and mutant NP71 | - |
Streptomyces hygroscopicus | - |
SF1293 | - |
Streptomyces hygroscopicus SF1293 | - |
SF1293 | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
carboxyphosphonoenolpyruvate | - |
Streptomyces hygroscopicus | (hydroxyphosphinyl)pyruvate + CO2 | - |
? | |
carboxyphosphonoenolpyruvate | first natural phosphinate | Streptomyces hygroscopicus | (hydroxyphosphinyl)pyruvate + CO2 | - |
? | |
carboxyphosphonoenolpyruvate | biosynthetic pathway that leads to the tripeptide antibiotic bialaphos, formation of one of the two C-P bonds in bialaphos | Streptomyces hygroscopicus | (hydroxyphosphinyl)pyruvate + CO2 | - |
? | |
carboxyphosphonoenolpyruvate | - |
Streptomyces hygroscopicus SF1293 | (hydroxyphosphinyl)pyruvate + CO2 | - |
? | |
carboxyphosphonoenolpyruvate | first natural phosphinate | Streptomyces hygroscopicus SF1293 | (hydroxyphosphinyl)pyruvate + CO2 | - |
? | |
carboxyphosphonoenolpyruvate | biosynthetic pathway that leads to the tripeptide antibiotic bialaphos, formation of one of the two C-P bonds in bialaphos | Streptomyces hygroscopicus SF1293 | (hydroxyphosphinyl)pyruvate + CO2 | - |
? |