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Literature summary for 2.7.8.11 extracted from

  • Carman, G.M.; Fischl, A.S.
    Phosphatidylinositol synthase from yeast (1992), Methods Enzymol., 209, 305-312.
    View publication on PubMed
Search for more literature for 2.7.8.11

Inhibitors

Inhibitors Comment Organism Structure
additional information inactivated by thioreactive reagents Saccharomyces cerevisiae

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.21
-
 myo-inositol pH 8.0, 37°C Saccharomyces cerevisiae

Localization

Localization Comment Organism GeneOntology No. Textmining
membrane
-
 Saccharomyces cerevisiae 16020
-
microsome
-
 Saccharomyces cerevisiae
-
-
mitochondrial membrane
-
 Saccharomyces cerevisiae 31966
-
mitochondrion
-
 Saccharomyces cerevisiae 5739
-
plasma membrane
-
 Saccharomyces cerevisiae 5886
-

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
CDP-diacylglycerol + myo-inositol Saccharomyces cerevisiae
-
 CMP + phosphatidyl-1D-myo-inositol
-
 r

Organism

Organism UniProt Comment Textmining
Saccharomyces cerevisiae
-
 yeast
-
Saccharomyces cerevisiae
-
 wild-type strain S288C(alpha gal2)
-

Purification (Commentary)

Purification (Comment) Organism
-
 Saccharomyces cerevisiae

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
0.8
-
-
 Saccharomyces cerevisiae

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
CDP-diacylglycerol + myo-inositol
-
 Saccharomyces cerevisiae CMP + phosphatidyl-1D-myo-inositol
-
 r

Temperature Stability [°C]

Temperature Stability Minimum [°C] Temperature Stability Maximum [°C] Comment Organism
60
-
 labile above Saccharomyces cerevisiae

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
8
-
-
 Saccharomyces cerevisiae