KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.14 | - |
UDP-glucose | non-galactosemic phenotype, pH 7.8, 37°C | Homo sapiens | |
0.18 | - |
diphosphate | non-galactosemic phenotype, pH 7.8, 37°C | Homo sapiens | |
0.18 | - |
UDP-glucose | galactosemic phenotype, pH 7.8, 37°C | Homo sapiens | |
0.2 | - |
diphosphate | galactosemic phenotype, pH 7.8, 37°C | Homo sapiens |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
Mg2+ | requirement | Homo sapiens |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
skin fibroblast | from normal and galactosemic individuals | Homo sapiens | - |
Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|
additional information | - |
- |
Homo sapiens |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
UTP + alpha-D-glucose 1-phosphate | - |
Homo sapiens | diphosphate + UDP-glucose | - |
r |
Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
---|---|---|---|
37 | - |
assay at | Homo sapiens |
Temperature Stability Minimum [°C] | Temperature Stability Maximum [°C] | Comment | Organism |
---|---|---|---|
50 | - |
15 min, about 10% or 25% loss of activity of enzymes from normal or galactosemic individuals, respectively | Homo sapiens |
56 | - |
t1/2: 4 min | Homo sapiens |
56 | - |
15 min: inactivation | Homo sapiens |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
7.3 | 8.6 | broad | Homo sapiens |