Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
cytosol | - |
Sus scrofa | 5829 | - |
endoplasmic reticulum | membrane of endoplasmic reticulum | Sus scrofa | 5783 | - |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Sus scrofa | I3LM39 | - |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
duodenum | mRNA is abundant in the spleen, duodenum, jejunum, and ileum | Sus scrofa | - |
ileum | mRNA is abundant in the spleen, duodenum, jejunum, and ileum | Sus scrofa | - |
jejunum | mRNA is abundant in the spleen, duodenum, jejunum, and ileum | Sus scrofa | - |
PK-15 cell | - |
Sus scrofa | - |
spleen | mRNA is abundant in the spleen, duodenum, jejunum, and ileum | Sus scrofa | - |
General Information | Comment | Organism |
---|---|---|
physiological function | the overexpression of wild-type cGAS in porcine kidney epithelial cells, but not its catalytically inactive mutants, induces IFN-beta expression, which is dependent on STING and IRF3. The downregulation of cGAS by RNAi markedly reduces IFN-beta expression after pseudorabies virus infection or poly(dA:dT) transfection | Sus scrofa |