Protein Variants | Comment | Organism |
---|---|---|
additional information | construction of a pnp inactivation mutant, comparative proteomic analysis and 81-176 phenotype, overview. Levels of peb3 and katA mRNA are significantly decreased in the pnp mutant strain compared to the parental strain, while gene expression of luxS and hsp90 remains unaffected by the pnp mutation, but not protein expression, overview. Poly(A) degradation by lysates of the pnp mutant strain is almost totally non-responsive to phosphate addition | Campylobacter jejuni |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
cytoplasm | - |
Campylobacter jejuni | 5737 | - |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Campylobacter jejuni | - |
strains 81-176 and F38011 | - |
Synonyms | Comment | Organism |
---|---|---|
PNPase | - |
Campylobacter jejuni |
polynucleotide phosphorylase | - |
Campylobacter jejuni |
Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
---|---|---|---|
37 | - |
assay at | Campylobacter jejuni |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
7 | - |
assay at | Campylobacter jejuni |
General Information | Comment | Organism |
---|---|---|
malfunction | the inactivation of the pnp gene reduces significantly the ability of Campylobacter jejuni to adhere and to invade Ht-29 cells, the mutant strain exhibits a decrease in swimming ability and chick colonization, 81-176 phenotype, overview. The pnp mutation do not induce profound proteomic changes suggesting that other ribonucleases in the organism might ensure this biological function in the absence of PNPase | Campylobacter jejuni |
physiological function | the role of PNPase is pleiotropic | Campylobacter jejuni |