Literature summary for 2.7.7.7 extracted from

Choi, J.J.; Song, J.G.; Nam, K.H.; Lee, J.I.; Bae, H.; Kim, G.A.; Sun, Y.; Kwon, S.T.
Unique substrate spectrum and PCR application of Nanoarchaeum equitans family B DNA polymerase (2008), Appl. Environ. Microbiol., 74, 6563-6569.

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Application

Application	Comment	Organism
diagnostics	the enzyme is useful in DNA amplification and PCR-based applications, particularly in clinical diagnoses using uracil-DNA glycosylase	Nanoarchaeum equitans
synthesis	the enzyme is useful in DNA amplification and PCR-based applications, particularly in clinical diagnoses using uracil-DNA glycosylase. A mixture of Nanoarchaeum equitans DNA polymerase and Thermus aquaticus DNA polymerase improves the performance of Neq DNA polymerase for long and accurate PCR	Nanoarchaeum equitans

Organism

Organism	UniProt	Comment	Textmining
Nanoarchaeum equitans	-	-	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
deoxynucleoside triphosphate + DNAn	the enzyme utilizes deaminated bases and is also able to amplify lambda DNA fragments using dUTP and dITP	Nanoarchaeum equitans	diphosphate + DNAn+1	-	?

Synonyms

Synonyms	Comment	Organism
Neq DNA polymerase	-	Nanoarchaeum equitans

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Release 2023.1 (January 2023)