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Literature summary for 2.7.7.65 extracted from

  • Wu, C.; Cheng, Y.Y.; Yin, H.; Song, X.N.; Li, W.W.; Zhou, X.X.; Zhao, L.P.; Tian, L.J.; Han, J.C.; Yu, H.Q.
    Oxygen promotes biofilm formation of Shewanella putrefaciens CN32 through a diguanylate cyclase and an adhesin (2013), Sci. Rep., 3, 1945.
    View publication on PubMedView publication on EuropePMC
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Organism

Organism UniProt Comment Textmining
Shewanella putrefaciens
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Shewanella putrefaciens CN32
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Synonyms

Synonyms Comment Organism
DosD
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 Shewanella putrefaciens

General Information

General Information Comment Organism
physiological function DosD is a direct oxygen-sensing diguanylate cyclase playing a regulatory role in biofilm formation by Shewanella putrefaciens CN32 under aerobic conditions. The activity of DosD culminates to synthesis of cyclic diguanylate in the presence of oxygen. DosD regulates the transcription of the bpfA operon which encodes seven proteins including a large repetitive adhesin BpfA and its cognate type I secretion system (TISS). Regulation of DosD in aerobic biofilms is heavily dependent on an adhesin BpfA and the TISS Shewanella putrefaciens