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Literature summary for 2.7.7.52 extracted from

  • Chung, C.; Jaramillo, J.; Ellis, M.; Bour, D.; Seidl, L.; Jo, D.; Turk, M.; Mann, M.; Bi, Y.; Haniford, D.; Duennwald, M.; Heinemann, I.
    RNA surveillance by uridylation-dependent RNA decay in Schizosaccharomyces pombe (2019), Nucleic Acids Res., 47, 3045-3057 .
    View publication on PubMedView publication on EuropePMC

Cloned(Commentary)

Cloned (Comment) Organism
expressed in Escherichia coli BL21 Codon Plus cells Schizosaccharomyces pombe

Organism

Organism UniProt Comment Textmining
Schizosaccharomyces pombe
-
-
-
Schizosaccharomyces pombe BG 0000H6
-
-
-

Purification (Commentary)

Purification (Comment) Organism
Ni-NTA resin column chromatography and Superdex 200 gel filtration Schizosaccharomyces pombe

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
UTP + miRNAn
-
Schizosaccharomyces pombe diphosphate + miRNAn+1
-
?
UTP + miRNAn
-
Schizosaccharomyces pombe BG 0000H6 diphosphate + miRNAn+1
-
?
UTP + mRNAn
-
Schizosaccharomyces pombe diphosphate + mRNAn+1
-
?
UTP + mRNAn
-
Schizosaccharomyces pombe BG 0000H6 diphosphate + mRNAn+1
-
?
UTP + poly(A) tail mimic RNAn
-
Schizosaccharomyces pombe diphosphate + poly(A) tail mimic RNAn+1
-
?
UTP + poly(A) tail mimic RNAn
-
Schizosaccharomyces pombe BG 0000H6 diphosphate + poly(A) tail mimic RNAn+1
-
?
UTP + pre-miRNAn
-
Schizosaccharomyces pombe diphosphate + pre-miRNAn+1
-
?
UTP + pre-miRNAn
-
Schizosaccharomyces pombe BG 0000H6 diphosphate + pre-miRNAn+1
-
?
UTP + tRNAn
-
Schizosaccharomyces pombe diphosphate + tRNAn+1
-
?
UTP + tRNAn
-
Schizosaccharomyces pombe BG 0000H6 diphosphate + tRNAn+1
-
?

Synonyms

Synonyms Comment Organism
caffeine-induced death suppressor protein 1
-
Schizosaccharomyces pombe
Cid1
-
Schizosaccharomyces pombe
terminal uridylyltransferase
-
Schizosaccharomyces pombe
TUTase
-
Schizosaccharomyces pombe

General Information

General Information Comment Organism
malfunction enzyme deletion increases sensitivity to protein misfolding stress Schizosaccharomyces pombe
metabolism the enzyme uridylates polyadenylated mRNAs to trigger Lsm1-7-mediated decapping of the RNA 5'-end and subsequent degradation by the U-specific exonuclease Dis3L2 Schizosaccharomyces pombe