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Literature summary for 2.7.7.50 extracted from

  • Ensinger, M.J.; Martin, S.A.; Paoletti, E.; Moss, B.
    Modification of the 5-terminus of mRNA by soluble guanylyl and methyl transferases from vaccinia virus (1975), Proc. Natl. Acad. Sci. USA, 72, 2525-2529.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 2.7.7.50

Localization

Localization Comment Organism GeneOntology No. Textmining
viral nucleocapsid
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 Vaccinia virus 19013
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Metals/Ions

Metals/Ions Comment Organism Structure
Mg2+ required Vaccinia virus
Mn2+ can partially replace Mg2+ in activation Vaccinia virus

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Vaccinia virus specific post-transcriptional modification of the 5'-terminus of mRNA ?
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 ?

Organism

Organism UniProt Comment Textmining
Vaccinia virus
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-
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Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
GTP + pp(5')RNA the acceptor is unmethylated vaccinia virus mRNA Vaccinia virus G(5')ppp(5')RNA + diphosphate guanosine residue linked 5' through three phosphates to the 5' position of the terminal residue ?
GTP + pp(5')RNA only the alpha-phosphate is transferred Vaccinia virus G(5')ppp(5')RNA + diphosphate guanosine residue linked 5' through three phosphates to the 5' position of the terminal residue ?
GTP + pp(5')RNA enzyme can modify synthetic poly(A) to form the structure m7G(5')ppp(5')AmP Vaccinia virus G(5')ppp(5')RNA + diphosphate guanosine residue linked 5' through three phosphates to the 5' position of the terminal residue ?
additional information specific post-transcriptional modification of the 5'-terminus of mRNA Vaccinia virus ?
-
 ?