Cloned (Comment) | Organism |
---|---|
expression in Escherichia coli | Human immunodeficiency virus 1 |
Protein Variants | Comment | Organism |
---|---|---|
additional information | the isolated RNase H domain of HIV-1 reverse transcriptase is inactive. Two chimeric proteins, carrying the hybrid binding domain of either Thermotoga maritima RNase H1 or Geobacillus stearothermophilus RNase H2 bind to RNA/DNA hybrids more strongly than the RNase H domain of HIV and exhibit enzymatic activity in the presence of Mn2+ ions. Activity in the presence of Mg2+ ions is very weak or absent | Human immunodeficiency virus 1 |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
Mn2+ | isolated RNase H domain, very weak activity in presence of Mn2+ | Human immunodeficiency virus 1 |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Human immunodeficiency virus 1 | - |
- |
- |