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Literature summary for 2.7.7.49 extracted from
- Strand transfer events during HIV-1 reverse transcription (2008), Virus Res., 134, 19-38.
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| additional information | Human immunodeficiency virus 1 | can use both RNA and DNA as a template for DNA synthesis and can cleave RNA within an RNA/DNA hybrid (RNase H activity) | ? | - |
? |  |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Human immunodeficiency virus 1 | - |
- |
- |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| deoxynucleoside triphosphate + DNAn | - |
Human immunodeficiency virus 1 | diphosphate + DNAn+1 | - |
? | |
| additional information | can use both RNA and DNA as a template for DNA synthesis and can cleave RNA within an RNA/DNA hybrid (RNase H activity) | Human immunodeficiency virus 1 | ? | - |
? | |
Subunits
| Subunits | Comment | Organism |
|---|---|---|
| heterodimer | consists of p66 and p51 subunits | Human immunodeficiency virus 1 |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| reverse transcriptase | exhibits DNA polymerase activity and RNase H activity | Human immunodeficiency virus 1 |
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