Cloned (Comment) | Organism |
---|---|
expression in Escherichia coli | Severe acute respiratory syndrome-related coronavirus |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
Mn2+ | strictly dependent on Mn2+ | Severe acute respiratory syndrome-related coronavirus |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Severe acute respiratory syndrome-related coronavirus | P0C6X7 | replicase polyprotein 1ab | - |
Purification (Comment) | Organism |
---|---|
recombinant protein | Severe acute respiratory syndrome-related coronavirus |
Storage Stability | Organism |
---|---|
-80°C, stable for at least 3 months | Severe acute respiratory syndrome-related coronavirus |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | enzyme shows both primer-dependent and primer-independent RNA synthesis activities using homopolymeric RNA templates. It preferentially copies homopolymeric pyrimidine RNA templates in the absence of an added oligonucleotide primer and is also able to initiate de novo RNA synthesis from the 3'-ends of both the plus- and minus-strand genome of human SARS coronavirus, using the 3'-terminal 36- and 37-nt RNA, respectively | Severe acute respiratory syndrome-related coronavirus | ? | - |
? |
Synonyms | Comment | Organism |
---|---|---|
nonstructural protein 12 | - |
Severe acute respiratory syndrome-related coronavirus |
nsp12 | - |
Severe acute respiratory syndrome-related coronavirus |
RDRP | - |
Severe acute respiratory syndrome-related coronavirus |