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Literature summary for 2.7.7.48 extracted from

  • Esmaeili, F.
    Enhancement of RNA interference effect in P19 EC cells by an RNA-dependent RNA polymerase (2009), Iran. Biomed. J., 13, 19-25.
    View publication on PubMed

Application

Application Comment Organism
molecular biology the enzyme, that is absent in mammalian cells, enhances the effect of siRNA expression on target gene expression in mammalian cells, when coexpressed, for amplifying the use of hairpin siRNA expression vectors for gene silencing, method development, overview Caenorhabditis elegans

Cloned(Commentary)

Cloned (Comment) Organism
expression of ego-1 in the P19 EC cell line derived of murine embryonal carcinoma stem cells, co-expression with si RNA leads to gene silencing that is enhanced by ego-1, overview Caenorhabditis elegans

Organism

Organism UniProt Comment Textmining
Caenorhabditis elegans
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Synonyms

Synonyms Comment Organism
ego-1
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Caenorhabditis elegans
RDRP
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Caenorhabditis elegans
RNA-dependent RNA polymerase
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Caenorhabditis elegans