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Literature summary for 2.7.7.48 extracted from
- Replication of viral nucleic acids. II. Inhibition of Q replicase by sulfhydryl-blocking reagents (1972), Biochim. Biophys. Acta, 281, 233-243.
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| HgCl2 | inhibition is reversed by incubation with an excess amount of dithiothreitol and 2-mercaptoethanol | Qubevirus durum |  |
| PCMB | inhibition is reversed by incubation with an excess amount of dithiothreitol and 2-mercaptoethanol. PCMB-inhibited enzyme is unable to synthesize RNA, but still maintains template-binding ability | Qubevirus durum | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Qubevirus durum | - |
Escherichia coli infected with | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| nucleoside triphosphate + RNAn | - |
Qubevirus durum | diphosphate + RNAn+1 | - |
? | |
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Release 2023.1 (January 2023)
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