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Literature summary for 2.7.7.41 extracted from

  • Lin, C.H.; Lin, J.; Strickland, K.P.
    Bovine brain microsomal CDP-diacylglycerol synthetase: solubilization and properties (1991), Biochem. Int., 25, 299-306.
    View publication on PubMed

Activating Compound

Activating Compound Comment Organism Structure
CHAPS maximal activity at 0.5% Bos taurus
phosphatidylcholine the solubilized but not the microsomal enzyme is activated Bos taurus

Inhibitors

Inhibitors Comment Organism Structure
5,5'-dithiobis(2-nitrobenzoic acid)
-
Bos taurus
cardiolipin the solubilized but not the microsomal enzyme is strongly inhibited Bos taurus
CHAPS at 0.3% Bos taurus
lysophosphatidylcholine the solubilized but not the microsomal enzyme is strongly inhibited Bos taurus
NEM
-
Bos taurus
PCMB
-
Bos taurus

Localization

Localization Comment Organism GeneOntology No. Textmining
microsome
-
Bos taurus
-
-

Organism

Organism UniProt Comment Textmining
Bos taurus
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
brain
-
Bos taurus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
CTP + phosphatidate phosphatidic acid from egg lecithin and 1-stearoyl 2-arachidonoyl phosphatidic acid are preferred substrates for the microsomal enzyme Bos taurus diphosphate + CDPdiacylglycerol
-
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