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Literature summary for 2.7.7.3 extracted from

  • Rubio, S.; Whitehead, L.; Larson, T.R.; Graham, I.A.; Rodriguez, P.L.
    The coenzyme a biosynthetic enzyme phosphopantetheine adenylyltransferase plays a crucial role in plant growth, salt/osmotic stress resistance, and seed lipid storage (2008), Plant Physiol., 148, 546-556.
    View publication on PubMedView publication on EuropePMC

Cloned(Commentary)

Cloned (Comment) Organism
expression of recombinant MBP-PPAT was induced with 1 mM isopropylthio-beta-galactoside in Escherichia coli DH5alpha cells Arabidopsis thaliana

Inhibitors

Inhibitors Comment Organism Structure
CoA
-
Arabidopsis thaliana

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
4'-phosphopantetheine + ATP Arabidopsis thaliana important enzyme in CoA biosynthesis 3'-dephospho-CoA + diphosphate
-
r

Organism

Organism UniProt Comment Textmining
Arabidopsis thaliana
-
-
-

Purification (Commentary)

Purification (Comment) Organism
the fusion protein was purified by amylose affinity chromatography Arabidopsis thaliana

Source Tissue

Source Tissue Comment Organism Textmining
seedling
-
Arabidopsis thaliana
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
4'-phosphopantetheine + ATP important enzyme in CoA biosynthesis Arabidopsis thaliana 3'-dephospho-CoA + diphosphate
-
r
4'-phosphopantetheine + Mg2+-ATP PPAT does not accept 4'-phosphopantothenoyl-Cys as a substrate Arabidopsis thaliana 3'-dephospho-CoA + diphosphate
-
r

Synonyms

Synonyms Comment Organism
4'-phosphopantetheine adenylyltransferase
-
Arabidopsis thaliana
phosphopantetheine adenylyltransferase
-
Arabidopsis thaliana
PPAT
-
Arabidopsis thaliana

IC50 Value

IC50 Value IC50 Value Maximum Comment Organism Inhibitor Structure
0.038
-
-
Arabidopsis thaliana CoA