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Literature summary for 2.7.7.3 extracted from

  • Aghajanian, S.; Worrall, D.M.
    Identification and characterization of the gene encoding the human phosphopantetheine adenylyltransferase and dephospho-CoA kinase bifunctional enzyme (CoA synthase) (2002), Biochem. J., 365, 13-18.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 2.7.7.3

Cloned(Commentary)

Cloned (Comment) Organism
expression in Escherichia coli BL21 Homo sapiens

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.0147
-
 3'-dephospho-CoA 25°C, pH 8 Sus scrofa
0.272
-
 diphosphate 25°C, pH 8 Sus scrofa

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
62000
-
 gel filtration Sus scrofa

Organism

Organism UniProt Comment Textmining
Homo sapiens Q13057
-
-
Sus scrofa Q8MIR4
-
-

Purification (Commentary)

Purification (Comment) Organism
to homogenity Sus scrofa

Source Tissue

Source Tissue Comment Organism Textmining
liver
-
 Sus scrofa
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + pantetheine 4'-phosphate
-
 Homo sapiens diphosphate + 3'-dephospho-CoA
-
 r
ATP + pantetheine 4'-phosphate
-
 Sus scrofa diphosphate + 3'-dephospho-CoA
-
 r

Subunits

Subunits Comment Organism
monomer 1 * 62000, gel filtration Sus scrofa