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Literature summary for 2.7.7.3 extracted from

  • Worrall, D.M.; Tubbs, P.K.
    A bifunctional enzyme complex in coenzyme A biosynthesis: purification of pantetheine phosphate adenylyltransferase and dephospho-CoA kinase (1983), Biochem. J., 215, 153-157.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 2.7.7.3

Localization

Localization Comment Organism GeneOntology No. Textmining
cytosol
-
 Rattus norvegicus 5829
-
cytosol
-
 Sus scrofa 5829
-

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
57000
-
 alpha2, 2 * 57000, SDS-PAGE Sus scrofa
115000
-
 gel filtration Sus scrofa

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
ATP + pantetheine 4'-phosphate Rattus norvegicus
-
 diphosphate + 3'-dephospho-CoA
-
 ?
ATP + pantetheine 4'-phosphate Sus scrofa
-
 diphosphate + 3'-dephospho-CoA
-
 ?

Organism

Organism UniProt Comment Textmining
Rattus norvegicus
-
-
-
Sus scrofa
-
-
-

Purification (Commentary)

Purification (Comment) Organism
-
 Sus scrofa

Source Tissue

Source Tissue Comment Organism Textmining
liver
-
 Rattus norvegicus
-
liver
-
 Sus scrofa
-

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
7.61
-
-
 Sus scrofa

Storage Stability

Storage Stability Organism
-20°C, 0.5 mg protein/ml, at least 1 month Sus scrofa

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + pantetheine 4'-phosphate
-
 Rattus norvegicus diphosphate + 3'-dephospho-CoA
-
 ?
ATP + pantetheine 4'-phosphate
-
 Sus scrofa diphosphate + 3'-dephospho-CoA
-
 ?

Subunits

Subunits Comment Organism
dimer alpha2, 2 * 57000, SDS-PAGE Sus scrofa

Synonyms

Synonyms Comment Organism
More with EC 2.7.1.24 part of a bifunctional enzyme with EC 2.7.1.24 Rattus norvegicus
More with EC 2.7.1.24 part of a bifunctional enzyme with EC 2.7.1.24 Sus scrofa

Temperature Optimum [°C]

Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
30
-
 assay at Rattus norvegicus
30
-
 assay at Sus scrofa

pI Value

Organism Comment pI Value Maximum pI Value
Sus scrofa chromatofocusing technique with a PBE 94 column and Polybuffer 74
-
 5.75