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Literature summary for 2.7.7.13 extracted from

  • Cronje, C.; George, G.M.; Fernie, A.R.; Bekker, J.; Kossmann, J.; Bauer, R.
    Manipulation of L-ascorbic acid biosynthesis pathways in Solanum lycopersicum: elevated GDP-mannose pyrophosphorylase activity enhances L-ascorbate levels in red fruit (2012), Planta, 235, 553-564.
    View publication on PubMed
Search for more literature for 2.7.7.13

Cloned(Commentary)

Cloned (Comment) Organism
gene MPG1, recombinant overexpression in Solanum lycopersicum ripe, fruits show enhanced L-ascorbate levels Saccharomyces cerevisiae
recombinant functional overexpression of Saccharomyces cerevisiae gene MPG1 in Solanum lycopersicum, fruits show 17-31fold enhanced enzyme activity and L-ascorbate levels Solanum lycopersicum

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
GTP + alpha-D-mannose 1-phosphate Solanum lycopersicum
-
 diphosphate + GDP-mannose
-
 ?
GTP + alpha-D-mannose 1-phosphate Saccharomyces cerevisiae
-
 diphosphate + GDP-mannose
-
 ?
GTP + alpha-D-mannose 1-phosphate Saccharomyces cerevisiae FY23
-
 diphosphate + GDP-mannose
-
 ?

Organism

Organism UniProt Comment Textmining
Saccharomyces cerevisiae P41940 a S288C strain
-
Saccharomyces cerevisiae FY23 P41940 a S288C strain
-
Solanum lycopersicum
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
fruit low enzyme activity levels in green and red fruits Solanum lycopersicum
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
GTP + alpha-D-mannose 1-phosphate
-
 Solanum lycopersicum diphosphate + GDP-mannose
-
 ?
GTP + alpha-D-mannose 1-phosphate
-
 Saccharomyces cerevisiae diphosphate + GDP-mannose
-
 ?
GTP + alpha-D-mannose 1-phosphate
-
 Saccharomyces cerevisiae FY23 diphosphate + GDP-mannose
-
 ?

Synonyms

Synonyms Comment Organism
GDP-mannose pyrophosphorylase
-
 Solanum lycopersicum
GDP-mannose pyrophosphorylase
-
 Saccharomyces cerevisiae
GMPase
-
 Solanum lycopersicum
GMPase
-
 Saccharomyces cerevisiae

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
7.5
-
 assay at Solanum lycopersicum
7.5
-
 assay at Saccharomyces cerevisiae

General Information

General Information Comment Organism
additional information overexpression of GDP-mannose pyrophosphorylase from Saccharomyces cerevisiae in red fruits of Solanum lycopersicum enhances L-ascorbate levels Solanum lycopersicum
additional information overexpression of GDP-mannose pyrophosphorylase in red fruits of Solanum lycopersicum enhances L-ascorbate levels Saccharomyces cerevisiae