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Literature summary for 2.7.7.1 extracted from

  • Atkinson, M.R.; Jackson, J.F.; Morton, R.K.
    Nicotinamide mononucleotide adenylyltransferase of pig-liver nuclei: the effects of nicotine mononucleotide concentration and pH on dinucleotide synthesis (1961), Biochem. J., 80, 318-323.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 2.7.7.1

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.0719
-
 NMN 25°C, pH 8.76 Sus scrofa
0.0752
-
 NMN 25°C, pH 7.95 Sus scrofa
0.0791
-
 NMN 25°C, pH 8.44 Sus scrofa
0.0877
-
 NMN 25°C, pH 7.63 Sus scrofa
0.0879
-
 NMN 25°C, pH 7.16 Sus scrofa
0.105
-
 NMN 25°C, pH 6.21 Sus scrofa
0.106
-
 NMN 25°C, pH 9.55 Sus scrofa
0.108
-
 NMN 25°C, pH 6.66 Sus scrofa
0.1129
-
 NMN 25°C, pH 9.4 Sus scrofa
0.139
-
 NMN 25°C, pH 5.85 Sus scrofa
0.18
-
 NMN 25°C, pH 10 Sus scrofa
0.187
-
 NMN 25°C, pH 5.53 Sus scrofa
0.201
-
 NMN 25°C, pH 9.77 Sus scrofa
0.298
-
 NMN 25°C, pH 10.35 Sus scrofa
0.336
-
 NMN 25°C, pH 10.55 Sus scrofa
0.45
-
 NMN 25°C, pH 5.15 Sus scrofa
0.594
-
 NMN 25°C, pH 4.95 Sus scrofa

Localization

Localization Comment Organism GeneOntology No. Textmining
nucleus
-
 Sus scrofa 5634
-

Metals/Ions

Metals/Ions Comment Organism Structure
Mg2+ requirement Sus scrofa

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
ATP + nicotinamide ribonucleotide Sus scrofa
-
 diphosphate + NAD+
-
 r

Organism

Organism UniProt Comment Textmining
Sus scrofa
-
-
-

Reaction

Reaction Comment Organism Reaction ID
ATP + nicotinamide ribonucleotide = diphosphate + NAD+ mechanism Sus scrofa
a

Source Tissue

Source Tissue Comment Organism Textmining
liver
-
 Sus scrofa
-

Storage Stability

Storage Stability Organism
-15°C, several months Sus scrofa

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + nicotinamide ribonucleotide
-
 Sus scrofa diphosphate + NAD+
-
 r
ATP + nicotinamide ribonucleotide i.e. NMN or nicotinamide mononucleotide Sus scrofa diphosphate + NAD+
-
 r

Temperature Optimum [°C]

Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
37
-
 assay at Sus scrofa