KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.026 | - |
GMP | pH 7.5, 37ºC | Homo sapiens | |
0.03 | - |
dGMP | pH 7.5, 37ºC | Homo sapiens | |
0.047 | - |
ganciclovir monophosphate | pH 7.5, 37ºC | Homo sapiens | |
0.052 | - |
(R)-ganciclovir phosphonate | pH 7.5, 37ºC | Homo sapiens |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Sus scrofa | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
brain | - |
Sus scrofa | - |
erythrocyte | - |
Homo sapiens | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + (R)-3-((2-amino-1,6-dihydro-6-oxo-9H-purin-9-yl)methoxy)-4-hydroxybutylphosphonic acid | i.e. R-ganciclovir phosphonate, (S) enantiomer 100fold less efficient, used for racemic resolution | Homo sapiens | (R)-ganciclovir phosphonate monophosphate | - |
? | |
ATP + (R)-3-((2-amino-1,6-dihydro-6-oxo-9H-purin-9-yl)methoxy)-4-hydroxybutylphosphonic acid | i.e. R-ganciclovir phosphonate, (S) enantiomer 100fold less efficient, used for racemic resolution | Sus scrofa | (R)-ganciclovir phosphonate monophosphate | - |
? | |
ATP + (R)-ganciclovir phosphonate | - |
Homo sapiens | ? | - |
? | |
ATP + ganciclovir monophosphate | - |
Homo sapiens | ? | - |
? |