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Literature summary for 2.7.4.3 extracted from

  • Camara, M.d.e..L.; Bouvier, L.A.; Canepa, G.E.; Miranda, M.R.; Pereira, C.A.
    Molecular and functional characterization of a Trypanosoma cruzi nuclear adenylate kinase isoform (2013), PLoS Negl. Trop. Dis., 7, e2044.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 2.7.4.3

Cloned(Commentary)

Cloned (Comment) Organism
the His6-tagged enzyme is expressed in Escherichia coli BL21(DE3) cells Trypanosoma cruzi

Localization

Localization Comment Organism GeneOntology No. Textmining
cytoplasm
-
 Trypanosoma cruzi 5737
-
nucleolus nucleolar localization is dependent on nutrient availability and active transcription and ribosome assembly and is lost upon oxidative stress Trypanosoma cruzi 5730
-
nucleus
-
 Trypanosoma cruzi 5634
-

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
25000
-
 x * 25000, SDS-PAGE Trypanosoma cruzi

Organism

Organism UniProt Comment Textmining
Trypanosoma cruzi
-
-
-

Purification (Commentary)

Purification (Comment) Organism
Ni-NTA bead chromatography, and glutathione Sepharose bead chromatography Trypanosoma cruzi

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + AMP
-
 Trypanosoma cruzi ADP + ADP
-
 r

Subunits

Subunits Comment Organism
? x * 25000, SDS-PAGE Trypanosoma cruzi

Synonyms

Synonyms Comment Organism
ADK
-
 Trypanosoma cruzi
ATP:AMP phosphotransferase
-
 Trypanosoma cruzi

General Information

General Information Comment Organism
physiological function nuclear adenylate kinase isoform is involved in ribosome biogenesis by performing ribosomal 18S RNA processing by direct interaction with ribosomal protein TcRps14 Trypanosoma cruzi