Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 2.7.4.3 extracted from

  • Schulze, D.U.; Duefer, M.; Wieringa, B.; Krippeit-Drews, P.; Drews, G.
    An adenylate kinase is involved in KATP channel regulation of mouse pancreatic beta cells (2007), Diabetologia, 50, 2126-2134.
    View publication on PubMed
Search for more literature for 2.7.4.3

Protein Variants

Protein Variants Comment Organism
additional information in adenylate kinase knock-out mice, the stimulatory effect of AMP on K/ATP channels is much less pronounced, though not completely suppressed Mus musculus

Inhibitors

Inhibitors Comment Organism Structure
adenosine 5'-(beta,gamma-imido)triphosphate tetralithium non-metabolizable ATP analogue, inhibition of adenylate kinase abolishes the stimulatory effect of AMP on K/ATP channels Mus musculus
P1,P5-di(adenosine-5')pentaphosphate inhibition of adenylate kinase prevents the stimulatory effect of AMP on K/ATP channels Mus musculus

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Mus musculus adenylte kinase-catalysed ADP production in the vicinity of K/ATP channels is involved in channel regulation ?
-
 ?

Organism

Organism UniProt Comment Textmining
Mus musculus
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
pancreas
-
 Mus musculus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information adenylte kinase-catalysed ADP production in the vicinity of K/ATP channels is involved in channel regulation Mus musculus ?
-
 ?