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Literature summary for 2.7.4.14 extracted from

  • Pearman, A.T.; Castro-Faria-Neto, H.C.; McIntyre, T.M.; Prescott, S.M.; Stafforini, D.M.
    Characterization of human UMP-CMP kinase enzymatic activity and 5' untranslated region (2001), Life Sci., 69, 2361-2370.
    View publication on PubMed

Metals/Ions

Metals/Ions Comment Organism Structure
Mg2+ strong requirement, maximal activity at 3 mM Homo sapiens

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
22222
-
x * 22222, calculation from nucleotide sequence Homo sapiens

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
ATP + CMP Homo sapiens the enzyme is required during rapid cell growth ADP + CDP
-
?

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
A-549 cell lung carcinoma Homo sapiens
-
bone marrow
-
Homo sapiens
-
Burkitt lymphoma cell
-
Homo sapiens
-
fetus
-
Homo sapiens
-
G-361 cell melanoma cell Homo sapiens
-
HeLa-S3 cell
-
Homo sapiens
-
K-562 cell chronic myelogenous leukemia cell Homo sapiens
-
leukocyte
-
Homo sapiens
-
liver
-
Homo sapiens
-
lymph node
-
Homo sapiens
-
macrophage
-
Homo sapiens
-
MOLT-4 cell lymphoblastic leukemia cell Homo sapiens
-
additional information two mRNA species are expressed in all immune tissues examined, an all cases the 3.4 kb form is the more prominent RNA species Homo sapiens
-
NCI-H660 cell promyelocytic leukemia Homo sapiens
-
peripheral blood mononuclear cell
-
Homo sapiens
-
RAJI cell
-
Homo sapiens
-
spleen
-
Homo sapiens
-
SW-480 cell colorectal adenocarcinoma cell Homo sapiens
-
thymus
-
Homo sapiens
-
vermiform appendix
-
Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + CMP
-
Homo sapiens ADP + CDP
-
?
ATP + CMP the enzyme is required during rapid cell growth Homo sapiens ADP + CDP
-
?
ATP + UMP
-
Homo sapiens ADP + UDP
-
?

Subunits

Subunits Comment Organism
? x * 22222, calculation from nucleotide sequence Homo sapiens