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Literature summary for 2.7.2.4 extracted from
- Aspartokinase of an extreme thermophile Thermus flavus partial purification and some properties (1977), Agric. Biol. Chem., 41, 1651-1655.
No PubMed abstract available
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| L-threonine | - |
Thermus thermophilus |  |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| ATP + L-aspartate | Thermus thermophilus | - |
ADP + 4-phospho-L-aspartate | - |
r | |
| ATP + L-aspartate | Thermus thermophilus AT-62 | - |
ADP + 4-phospho-L-aspartate | - |
r | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Thermus thermophilus | - |
AT-62 | - |
| Thermus thermophilus AT-62 | - |
AT-62 | - |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
| partial | Thermus thermophilus |
Specific Activity [micromol/min/mg]
| Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
|---|---|---|---|
| 58.6 | - |
- |
Thermus thermophilus |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| ATP + L-aspartate | - |
Thermus thermophilus | ADP + 4-phospho-L-aspartate | - |
r | |
| ATP + L-aspartate | - |
Thermus thermophilus AT-62 | ADP + 4-phospho-L-aspartate | - |
r | |
Temperature Optimum [°C]
| Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
|---|---|---|---|
| 75 | - |
- |
Thermus thermophilus |
Temperature Range [°C]
| Temperature Minimum [°C] | Temperature Maximum [°C] | Comment | Organism |
|---|---|---|---|
| 40 | 80 | - |
Thermus thermophilus |
Temperature Stability [°C]
| Temperature Stability Minimum [°C] | Temperature Stability Maximum [°C] | Comment | Organism |
|---|---|---|---|
| 70 | 85 | very heat stable, not inactivated after 30 min at 70°C, 30% of the original activity is lost after 30 min at 80°C, rapid inactivation above 85°C | Thermus thermophilus |
pH Optimum
| pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|
| 7 | 8 | - |
Thermus thermophilus |
pH Range
| pH Minimum | pH Maximum | Comment | Organism |
|---|---|---|---|
| 5.5 | 10 | - |
Thermus thermophilus |
pH Stability
| pH Stability | pH Stability Maximum | Comment | Organism |
|---|---|---|---|
| 5.5 | 10 | stable at slight alkali to acidic pH range, most stable at about pH 7.0, unstable at high alkali pH range, losing 90% of its original activity after 30 min at 70°C at pH 10.0 | Thermus thermophilus |
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