Inhibitors | Comment | Organism | Structure |
---|---|---|---|
5,5'-dithiobis(2-nitrobenzoic acid) | reversible | Fasciola hepatica | |
ADP | noncompetitive with respect to ATP and 3-phospho-D-glycerate | Fasciola hepatica | |
iodoacetamide | irreversible | Fasciola hepatica | |
N-ethylmaleimide | irreversible | Fasciola hepatica | |
p-chloromercuribenzoate | reversible | Fasciola hepatica |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.9 | - |
ATP | - |
Fasciola hepatica | |
1.26 | - |
3-phospho-D-glycerate | - |
Fasciola hepatica |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
47900 | - |
sedimentation equilibrium method | Fasciola hepatica |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Fasciola hepatica | - |
- |
- |
Purification (Comment) | Organism |
---|---|
375fold to homogeneity | Fasciola hepatica |
Reaction | Comment | Organism | Reaction ID |
---|---|---|---|
ATP + 3-phospho-D-glycerate = ADP + 3-phospho-D-glyceroyl phosphate | sequential mechanism | Fasciola hepatica |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + 3-phospho-D-glycerate | - |
Fasciola hepatica | ADP + 1,3-diphosphoglycerate | - |
r |
Subunits | Comment | Organism |
---|---|---|
monomer | 1 * 47900, SDS-PAGE | Fasciola hepatica |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
ADP | - |
Fasciola hepatica | |
ATP | required as phosphate donor | Fasciola hepatica |