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Literature summary for 2.7.12.1 extracted from

  • Arque, G.; de Lagran, M.M.; Arbones, M.L.; Dierssen, M.
    Age-associated motor and visuo-spatial learning phenotype in Dyrk1A heterozygous mutant mice (2009), Neurobiol. Dis., 36, 312-319.
    View publication on PubMed

Organism

Organism UniProt Comment Textmining
Mus musculus
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Synonyms

Synonyms Comment Organism
dual-specificity tyrosine-regulated kinase 1A
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Mus musculus
DYRK1A
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Mus musculus

General Information

General Information Comment Organism
malfunction heterozygous mice for Dyrk1A show marked alterations in traction ability, prehensile reflex and balance, but only present a slight impairment of visuo-spatial memory even though they show a robust decrease of CA1, CA2, CA3 and dentate gyrus cells Mus musculus