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Literature summary for 2.7.12.1 extracted from

  • Mazmanian, G.; Kovshilovsky, M.; Yen, D.; Mohanty, A.; Mohanty, S.; Nee, A.; Nissen, R.M.
    The zebrafish dyrk1b gene is important for endoderm formation (2010), Genesis, 48, 20-30.
    View publication on PubMedView publication on EuropePMC

Organism

Organism UniProt Comment Textmining
Danio rerio
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Source Tissue

Source Tissue Comment Organism Textmining

Synonyms

Synonyms Comment Organism
dual-specificity tyrosine-regulated kinase
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Danio rerio
DYRK1B
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Danio rerio

General Information

General Information Comment Organism
malfunction dyrk1b antisense morpholino knockdown animals reveal modestly expanded expression of the dorsal axial mesoderm marker gsc while the pan-mesodermal marker bik is largely unaffected, show moderately reduced endodermal markers cas and sox17, and reduced expression of the pharyngeal pouch marker edn1 Danio rerio
physiological function the zebrafish dyrk1b gene is important for endoderm formation, craniofacial patterning, and ndr2 expression Danio rerio