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Literature summary for 2.7.12.1 extracted from
- Expression of TTK, a novel human protein kinase, is associated with cell proliferation (1992), J. Biol. Chem., 267, 16000-16006.
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| additional information | Homo sapiens | the enzyme is associated with cell proliferation | ? | - |
? |  |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Homo sapiens | P33981 | - |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| cell culture | most malignant tumors assessed express TTK mRNA, as well, all rapidly proliferating cell lines tested express TTK mRNA | Homo sapiens | - |
| testis | - |
Homo sapiens | - |
| thymus | - |
Homo sapiens | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| ATP + protein | can phosphorylate serine, threonine, and tyrosine hydroxyamino acids | Homo sapiens | ADP + phosphoprotein | - |
? | |
| additional information | the enzyme is associated with cell proliferation | Homo sapiens | ? | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| dual specificity protein kinase TTK | - |
Homo sapiens |
| TTK | - |
Homo sapiens |
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