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Literature summary for 2.7.11.7 extracted from

  • Ravid, S.; Spudich, J.A.
    Membrane-bound Dictyostelium myosin heavy chain kinase: a developmentally regulated substrate-specific member of the protein kinase C family (1992), Proc. Natl. Acad. Sci. USA, 89, 5877-5881.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 2.7.11.7

Cloned(Commentary)

Cloned (Comment) Organism
DNA sequence determination and analysis, gene MHCK possesses all of the domains characteristic of members of the protein kinase C family Dictyostelium discoideum

Localization

Localization Comment Organism GeneOntology No. Textmining
membrane bound Dictyostelium discoideum 16020
-

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
ATP + myosin heavy chain kinase Dictyostelium discoideum intramolecular autophosphorylation ADP + myosin heavy chain kinase phosphate
-
 ?
ATP + myosin heavy chain kinase Dictyostelium discoideum increased activity during chemotaxis ADP + myosin heavy chain kinase phosphate
-
 ?
ATP + myosin heavy chain kinase Dictyostelium discoideum AX3 intramolecular autophosphorylation ADP + myosin heavy chain kinase phosphate
-
 ?
ATP + myosin heavy chain kinase Dictyostelium discoideum AX3 increased activity during chemotaxis ADP + myosin heavy chain kinase phosphate
-
 ?

Organism

Organism UniProt Comment Textmining
Dictyostelium discoideum P34125
-
-
Dictyostelium discoideum P34125 gene MHCK
-
Dictyostelium discoideum AX3 P34125
-
-

Source Tissue

Source Tissue Comment Organism Textmining
additional information enzyme expression only during development Dictyostelium discoideum
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + myosin heavy chain kinase intramolecular autophosphorylation Dictyostelium discoideum ADP + myosin heavy chain kinase phosphate
-
 ?
ATP + myosin heavy chain kinase enzyme incorporates 20 mol phosphate per mol of kinase Dictyostelium discoideum ADP + myosin heavy chain kinase phosphate
-
 ?
ATP + myosin heavy chain kinase the enzyme contains a cluster of 23 serine and threonine residues at the carboxyterminal end that might be the autophosphorylation domain Dictyostelium discoideum ADP + myosin heavy chain kinase phosphate
-
 ?
ATP + myosin heavy chain kinase increased activity during chemotaxis Dictyostelium discoideum ADP + myosin heavy chain kinase phosphate
-
 ?
ATP + myosin heavy chain kinase intramolecular autophosphorylation Dictyostelium discoideum AX3 ADP + myosin heavy chain kinase phosphate
-
 ?
ATP + myosin heavy chain kinase enzyme incorporates 20 mol phosphate per mol of kinase Dictyostelium discoideum AX3 ADP + myosin heavy chain kinase phosphate
-
 ?
ATP + myosin heavy chain kinase the enzyme contains a cluster of 23 serine and threonine residues at the carboxyterminal end that might be the autophosphorylation domain Dictyostelium discoideum AX3 ADP + myosin heavy chain kinase phosphate
-
 ?
ATP + myosin heavy chain kinase increased activity during chemotaxis Dictyostelium discoideum AX3 ADP + myosin heavy chain kinase phosphate
-
 ?

Synonyms

Synonyms Comment Organism
MHCK
-
 Dictyostelium discoideum

Cofactor

Cofactor Comment Organism Structure
ATP
-
 Dictyostelium discoideum