Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 2.7.11.4 extracted from

  • Xu, M.; Kitaura, Y.; Ishikawa, T.; Kadota, Y.; Terai, C.; Shindo, D.; Morioka, T.; Ota, M.; Morishita, Y.; Ishihara, K.; Shimomura, Y.
    Endurance performance and energy metabolism during exercise in mice with a muscle-specific defect in the control of branched-chain amino acid catabolism (2017), PLoS ONE, 12, e0180989 .
    View publication on PubMedView publication on EuropePMC
Search for more literature for 2.7.11.4

Organism

Organism UniProt Comment Textmining
Mus musculus O55028
-
-

Source Tissue

Source Tissue Comment Organism Textmining
muscle
-
 Mus musculus
-

Synonyms

Synonyms Comment Organism
BCKA dehydrogenase kinase
-
 Mus musculus
BDK
-
 Mus musculus

General Information

General Information Comment Organism
malfunction the endurance performance enhanced by 2 weeks of running training is somewhat, but significantly less in BDK-mKO mice than in control mice. Skeletal muscle of BDK-mKO mice has low levels of glycogen. Catabolism of branched-chain amino acids (BCAAs) is greatly enhanced in the muscle of BDK-mKO mice and produces branched-chain acyl-carnitine, which induces perturbation of energy metabolism in the muscle Mus musculus